UHP Grade | HP+
Grade | Electrolyte Grade
| PrecisionPure Consistency
| MSDS | Trace
Metals Results | Process
Performance: Finished Product vs. Raw Material
Acetonitrile PurityCritical in Many Applications
Acetonitrile is a critical solvent for several important
technologies. It is widely used as a mobile phase solvent in HPLC and
process chromatography applications, as a wash and reagent solution solvent
for oligonucleotide synthesis, and as an electrolyte component for certain
lithium batteries and ultracapacitors. In all of these applications, the
purity and consistency of the acetonitrile is vital to process or product
Industrial grades of acetonitrile are produced as a by-product
of acrylonitrile manufacturing. The initial by-product material is highly
contaminated and only contains about 60% acetonitrile. The most common
impurities are nitriles, aromatics, carbonyls, heterocycles and water.
Commercial acetonitrile grades are produced from these industrial byproduct
streams and contain residual levels of these impurities plus additional
contaminants from shipment and handling.
The impurities found in commercial acetonitrile
grades may cause problems in sensitive products or processes by causing
undesirable side reactions, by binding to separation media or complex
biomolecules or by interfering with detectors.
PTI purifies acetonitrile and removes these residual impurities using
an innovative, patented process. Acetonitrile purified by this special
process is given the tradename PrecisionPure and is characterized
by exceptionally low levels of water and trace organic impurities.
PrecisionPure Acetnonitrile means you can rely on the
highest purity standards for use in HPLC (analytical and process scale),
oligonucleotide synthesis, organic synthesis, electrolye manufacture and
semiconductor applications. Strict process controls and analytical testing
assure consistent product purity. This purity is maintained direct to
your facility through use of special transfer equipment and dedicated
Because it is a byproduct, supplies of commercial acetonitrile are often
tight and market shortages have occurred frequently. Quality varies significantly
among different suppliers or even from different facilities. Only PTI
consistently purifies acetonitrile from a variety of sources to the same
rigorous quality standard. Users can depend on both purity and reliable
delivery. That's important for products or processes governed by strict
parameters and/or regulatory requirements.
Two primary grades of PrecisionPure Acetonitrile are
produced using our unique process:
PrecisionPure UHP For
the most demanding analytical and process applications, with ultra low
water, under 5 ppm, and trace organics held to low ppb levels by HPLC.
UHP is the highest purity bulk acetonitrile available.
PrecisionPure HP Plus For
processes such as peptide purification, pharmaceutical synthesis and
separations where consistent purity and process cost are critical. Purified
using the same process but under more economical conditions, HP Plus
has a water specification of less than 50 ppm and trace organics held
to low levels by UV.
PTI works to satisfy every customer's specific needs and
often certifies material according to exact requirements. Please contact
us for additional information.
The links below show analytical and statistical data that
demonstrate the quality and consistency of PrecisionPure Acetonitrile.
We show the consistency of key parameters and the purity differences between
commercial grades and PTI grades. Links are also provided for specifications,
MSDS and physical data.
See for yourself how PrecisionPure Acetonitrile can
assure you of the purity and the reliable supply you need.
PrecisionPure UHP Acetonitrile:
Specifications, Typical UV, HPLC, Gradient
PrecisionPure HP+ Acetonitrile:
Specifications, Typical UV
Process Performance: Finished
Product vs. Raw Material
UV, Moisture, Gradient
PrecisionPure Trace Metals
PrecisionPure Electrolyte Acetonitrile:
Material Safety Data Sheet (MSDS)
For further information on PrecisionPure Acetonitrile,
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